It was a less than successful night in Europe for the two Manchester clubs as United had to settle for a home draw against Portugese side Benfica while Roberto Mancini’s Manchester City were beaten 2-1 by Napoli.
Sir Alex Ferguson’s side fell behind to a Phil Jones own goal after just four minutes but then took the lead at Old Trafford thanks to goals from Dimitar Berbatov and Darren Fletcher.
But a mistake by United keeper David De Gea allowed Pablo Aimar to snatch an equaliser for the visitors.
Italian international Mario Balotelli was on the scoresheet for City in Naples but a brace from Edinson Cavani saw the Serie A side run out 2-1 winners.
The Blues now face an uphill battle to progress in the Champions League.
They need to beat Group A winners Bayern Munich at Eastlands on December 7 to stand any chance of progression.
They must also hope Villarreal can take at least a point off Napoli in Spain.
need a point in their last Champions League Group C game against Basel if they are to ensure qualification to the knockout stages after the draw with Benfica.